At Carilion Clinic, a non-profit integrated healthcare delivery system, based in Roanoke, VA, is spreading the health benefits of physical activity to patients and healthcare employees through the use of a physician referral, exercise prescription program (FIT Rx) modeled after Exercise is Medicine®. As a medically-supervised program, FIT Rx includes personal training sessions, wellness center membership, and physician feedback throughout the entire process. Since its inception in 2011, more than 4,000 patients have been referred by their physicians. Recently, EHR access was provided to personal trainers to document session activity, which has improved the referral process and supports a team-based care approach. The original FIT Rx program has been now been expanded (FIT Rx 90) to specifically target physical activity and weight loss in Carilion employees.